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Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity

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Abstract Background Both the type I insulin-like growth factor receptor (IGF1R) and Src pathways are associated with the development and progression of numerous types of human cancer. and Src activation confers resistance to anti-IGF1R therapies. Hence. targeting both IGF1R and Src concurrently is one of the main challenges in combating resistance to the currently available anti-IGF1R... https://danddcollectiblers.shop/product-category/kids-nutritional-health/
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