Bacterial immune systems. such as CRISPR-Cas or restriction-modification (R-M) systems. affect bacterial pathogenicity and antibiotic resistance by modulating horizontal gene flow. A model system for CRISPR-Cas regulation. https://www.spidertattooz.com/BON-VIV-Spiked-Seltzer-Grapefruit-6pk-12oz-Can-4-5-ABV/